Some anti-cancer drugs are known for their potential to cause infusion reactions. Allergic infusions reaction, such as hypersensitivity can lead to anaphylaxis which may present with symptoms including cyanosis and loss of consciousness. Anaphylaxis is considered an oncological emergency and can be life-threatening.
It is important that all health professionals are able to:


  • recognise the signs and symptoms of infusion reactions, hypersensitivity and anaphylaxis
  • assess the severity of the reaction
  • initiate the right interventions and escalate care appropriately.


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Practical resources

The following resources and information can assist you in caring for patients with Infusion reactions:

Additional resources

For more in-depth information see the ESMO Handbook of Oncological Emergencies

Australasian Society of Clinical Immunology and Allergy (ASCIA) health professional information- Anaphylaxis

Allergy/World Allergy Organization Anaphylaxis Guidance 2020 position paper 

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